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Antipsychotic medications resulting in weight gain for which the later switch to aripiprazole was undertaken were distributed as follows: olanzapine 352 (46%), risperidone 226 (30%), typical—first generation 168 (22%), sulpiride 17 (3%), clozapine 11 (1%), and quetiapine 10 (1%). Talk with the doctor: There are several newer antipsychotics that are thought to have less weight gain like lurasidone, asenapine, iloperidone and ziprasidone. You may want to talk to the prescribing doctor to see if one is appropriate for you! 4791 views Reviewed >2 years ago


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5% of patients in the MDD trial saw weight gain (7% or more of body weight) 10% -11% of patients in the schizophrenia trial experienced weight gain (7% or more of body weight) Weight gain was measured by long term studies as well. MDD Results. Rexulti was discontinued Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics. Geodon (ziprasidone) treats bipolar disorder and schizophrenia with fewer side effects than similar medications, but has a risk of abnormal heart rhythm.